Zinc finger E-box binding homeobox 2 (Q8063006)

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mammalian protein found in Homo sapiens

zinc finger E-box-binding homeobox 2
SMAD interacting protein 1
Zinc finger homeobox protein 1b
ZEB2
zinc finger homeobox 1b
Smad-interacting protein 1
SMADIP1

Language	Label	Description	Also known as
English	Zinc finger E-box binding homeobox 2	mammalian protein found in Homo sapiens	zinc finger E-box-binding homeobox 2 SMAD interacting protein 1 Zinc finger homeobox protein 1b ZEB2 zinc finger homeobox 1b Smad-interacting protein 1 SMADIP1

Statements

1 reference

13 November 2019

UniProt protein ID

Homeobox-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60315

Zinc finger C2H2 superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60315

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drought induced 19 protein type, zinc-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

2 references

phosphatase regulator activity

determination method

1 reference

8 April 2019

Smad-interacting protein 1 is a repressor of liver/bone/kidney alkaline phosphatase transcription in bone morphogenetic protein-induced osteogenic differentiation of C2C12 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

protein binding

determination method

1 reference

8 April 2019

Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

nucleic acid binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

1 reference

8 April 2019

Regulation of the expression and activity of the antiangiogenic homeobox gene GAX/MEOX2 by ZEB2 and microRNA-221

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

sequence-specific DNA binding

determination method

1 reference

8 April 2019

Regulation of the expression and activity of the antiangiogenic homeobox gene GAX/MEOX2 by ZEB2 and microRNA-221

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

biological process

regulation of transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60315&geneProductId=UniProtKB:O60315

determination method

nervous system development

determination method

1 reference

8 April 2019

Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60315&geneProductId=UniProtKB:O60315

determination method

positive regulation of melanin biosynthetic process

determination method

1 reference

8 April 2019

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

negative regulation of transcription by RNA polymerase II

determination method

4 references

8 April 2019

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

Multiple tumor suppressor pathways negatively regulate telomerase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

8 April 2019

Regulation of the expression and activity of the antiangiogenic homeobox gene GAX/MEOX2 by ZEB2 and microRNA-221

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

neural crest cell migration

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

neural tube closure

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

transcription by RNA polymerase II

determination method

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60315&geneProductId=UniProtKB:O60315

determination method

central nervous system development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

corpus callosum morphogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

hippocampus development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

cell proliferation in forebrain

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

corticospinal tract morphogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

positive regulation of Wnt signaling pathway

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

positive regulation of JUN kinase activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

embryonic morphogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

collateral sprouting

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

positive regulation of axonogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

mammillary axonal complex development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

positive regulation of lens fiber cell differentiation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60315

determination method

Gene Atlas image

PBB GE ZEB2 203603 s at fs.png
732 × 530; 11 KB

0 references

Homeobox domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60315

Drought induced 19 protein type, zinc-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60315

Zinc finger C2H2-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60315

Identifiers

MeSH descriptor ID

subject named as

Zinc Finger E-box Binding Homeobox 2

0 references

D12.776.260.400.883

0 references

D12.776.260.703.700

0 references

D12.776.930.780.918

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000386854

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000386854

ENSP00000443792

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000443792

ENSP00000454157

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454157

ENSP00000487174

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487174

ENSP00000302501

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000302501

ENSP00000376601

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000376601

ENSP00000387256

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000387256

ENSP00000394777

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394777

ENSP00000395496

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395496

ENSP00000399451

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000399451

ENSP00000400993

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400993

ENSP00000475267

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475267

ENSP00000475329

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475329

ENSP00000475400

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475400

ENSP00000475502

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475502

ENSP00000475553

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475553

ENSP00000486240

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486240

ENSP00000486341

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486341

ENSP00000486346

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486346

ENSP00000487261

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487261

ENSP00000487476

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487476

ENSP00000489701

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000489701

ENSP00000490141

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490141

ENSP00000490175

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490175

ENSP00000490293

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490293

ENSP00000490317

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490317

ENSP00000490508

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490508

ENSP00000490673

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490673

ENSP00000490723

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490723

ENSP00000490776

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490776

ENSP00000490851

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490851

ENSP00000490872

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490872

ENSP00000490934

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490934

ENSP00000492572

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492572

ENSP00000494820

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000494820

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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