Superoxide dismutase 2 (Q7392025)

Manganese/iron superoxide dismutase, N-terminal domain superfamily

1 reference

Manganese/iron superoxide dismutase

1 reference

Manganese/iron superoxide dismutase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Manganese/iron superoxide dismutase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Manganese/iron superoxide dismutase, binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

superoxide dismutase activity

6 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

26 September 2017

Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

26 September 2017

Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

26 September 2017

Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

manganese ion binding

2 references

oxidoreductase activity

1 reference

8 April 2019

superoxide dismutase activity

IEA

7 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

1 January 2018

Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

1 January 2018

Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

1 January 2018

Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

superoxide dismutase activity

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

Nitric oxide enhances the manganese superoxide dismutase-dependent suppression of proliferation in HT-1080 fibrosarcoma cells

manganese ion binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

cell component

extracellular exosome

4 references

8 April 2019

8 April 2019

Nitric oxide enhances the manganese superoxide dismutase-dependent suppression of proliferation in HT-1080 fibrosarcoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

LYRM7/MZM1L is a UQCRFS1 chaperone involved in the last steps of mitochondrial Complex III assembly in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

negative regulation of neuron apoptotic process

HDA

biological process

1 reference

8 April 2019

Suppression of mitochondrial oxidative stress provides long-term neuroprotection in experimental optic neuritis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress

IGI

response to superoxide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Overexpression of manganese superoxide dismutase selectively modulates the activity of Jun-associated transcription factors in fibrosarcoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

removal of superoxide radicals

1 reference

8 April 2019

Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

regulation of blood pressure

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

ISS

1 reference

8 April 2019

Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

protein homotetramerization

1 reference

8 April 2019

Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

1 reference

8 April 2019

Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

release of cytochrome c from mitochondria

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

superoxide metabolic process

ISS

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

8 April 2019

Differential effects of superoxide dismutase isoform expression on hydroperoxide-induced apoptosis in PC-12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

negative regulation of cell population proliferation

1 reference

8 April 2019

Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

positive regulation of cell migration

1 reference

8 April 2019

Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

mitochondrion organization

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

cellular response to oxidative stress

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

interleukin-12-mediated signaling pathway

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04179&geneProductId=UniProtKB:P04179

negative regulation of vascular associated smooth muscle cell proliferation

1 reference

8 April 2019

MiR-140-5p regulates hypoxia-mediated human pulmonary artery smooth muscle cell proliferation, apoptosis and differentiation by targeting Dnmt1 and promoting SOD2 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

positive regulation of vascular associated smooth muscle cell apoptotic process

1 reference

8 April 2019

MiR-140-5p regulates hypoxia-mediated human pulmonary artery smooth muscle cell proliferation, apoptosis and differentiation by targeting Dnmt1 and promoting SOD2 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching

1 reference

8 April 2019

MiR-140-5p regulates hypoxia-mediated human pulmonary artery smooth muscle cell proliferation, apoptosis and differentiation by targeting Dnmt1 and promoting SOD2 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04179

Manganese/iron superoxide dismutase, C-terminal

Gene Atlas image

PBB GE SOD2 215223 s at fs.png
732 × 530; 10 KB

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has part(s)

1 reference

Manganese/iron superoxide dismutase, binding site

1 reference

Manganese/iron superoxide dismutase, N-terminal

1 reference

Identifiers

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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13 November 2019

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016