midostaurin (Q6842945)

Midostaurin (English)

18 November 2016

chemical formula

C₃₅H₃₀N₄O₄

1 reference

Midostaurin (English)

18 November 2016

canonical SMILES

CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC

1 reference

Midostaurin (English)

18 November 2016

isomeric SMILES

CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)C9=CC=CC=C9

1 reference

UNII

ID912S5VON

World Health Organisation international non-proprietary name

14 February 2018

midostaurin (English)

2 references

midostaurin (English)

medical condition treated

19 October 2016

published in

Recommended INN: List 41

publication date

1999

acute myeloid leukemia

1 reference

Drug Indications Extracted from FAERS

Food and Drug Administration

2 October 2018

acute myeloid leukemia

start time

28 April 2017

approved by

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/ID912S5VON

2 November 2018

reference URL

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207997s000lbl.pdf

physically interacts with

fms related receptor tyrosine kinase 3

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5702

LiverTox likelihood score

17 August 2016

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Midostaurin

10 April 2019

1 reference

https://www.novartis.com/about/products

subject has role

protein kinase inhibitors

1 reference

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

15 March 2018

C1872

1 reference

InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1

14 February 2018

Midostaurin

0 references

Identifiers

InChI

1 reference

Midostaurin (English)

BMGQWWVMWDBQGC-IIFHNQTCSA-N

18 November 2016

InChIKey

2 references

Midostaurin (English)

18 November 2016

14 February 2018

1 reference

14 February 2018

1 reference

Midostaurin (English)

18 November 2016

1 reference

Midostaurin (English)

18 November 2016

Reaxys registry number

7345336

1 reference

midostaurin (English)

19 October 2016

ChEBI ID

63452

mapping relation type

2 references

MIDOSTAURIN (English)

18 November 2016

ChEBI release 2021-03-01

1 reference

DSSTOX compound identifier

MIDOSTAURIN (English)

18 November 2016

1 reference

0 references

0 references

0 references

0 references

1 reference

https://www.whocc.no/atc_ddd_index/?code=L01XE39

World Health Organisation international non-proprietary name numeric ID

7677

1 reference

reference URL

https://mednet-communities.net/inn/db/ViewINN.aspx?i=7677

Guide to Pharmacology Ligand ID

5702

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5702

midostaurin (English)

18 November 2016

midostaurin

1 reference

Medical Subject Headings

14 March 2018

1 reference

14 February 2018

1 reference

Midostaurin (English)

3 July 2018

1 reference

UNII

ID912S5VON

MedlinePlus drug identifier

14 February 2018

0 references

1 reference

26 February 2018

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

midostaurin (English)

19 October 2016

0 references

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference