Glutathione S-transferase alpha 1 (Q5572461)

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mammalian protein found in Homo sapiens

• GSTA1
• GST-epsilon
• glutathione S-transferase Ha subunit 1
• GTH1
• 13-hydroperoxyoctadecadienoate peroxidase
• GSTA1-1
• GST class-alpha member 1
• glutathione S-transferase 2
• GST HA subunit 1
• glutathione S-transferase A1
• androst-5-ene-3,17-dione isomerase
• glutathione S-alkyltransferase A1
• S-(hydroxyalkyl)glutathione lyase A1
• glutathione S-aryltransferase A1
• testicular tissue protein Li 80

edit

Language	Label	Description	Also known as
English	Glutathione S-transferase alpha 1	mammalian protein found in Homo sapiens	GSTA1 GST-epsilon glutathione S-transferase Ha subunit 1 GTH1 13-hydroperoxyoctadecadienoate peroxidase GSTA1-1 GST class-alpha member 1 glutathione S-transferase 2 GST HA subunit 1 glutathione S-transferase A1 androst-5-ene-3,17-dione isomerase glutathione S-alkyltransferase A1 S-(hydroxyalkyl)glutathione lyase A1 glutathione S-aryltransferase A1 testicular tissue protein Li 80

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08263

part of

Glutathione S-transferase, alpha class

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08263

Thioredoxin-like superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08263

Glutathione S-transferase, C-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08263

Glutathione S-transferase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glutathione S-transferase, C-terminal-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glutathione S-transferase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08263

encoded by

GSTA1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08263

molecular function

transferase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

glutathione peroxidase activity

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

glutathione transferase activity

determination method

IEA

IDA

NAS

TAS

6 references

retrieved

1 January 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

TAS

retrieved

1 January 2018

stated in

Isolation and characterization of a human glutathione S-transferase Ha1 subunit gene

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

NAS

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IEA

retrieved

1 January 2018

stated in

The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

1 January 2018

stated in

Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IDA

glutathione transferase activity

determination method

IDA

IEA

NAS

6 references

retrieved

8 April 2019

stated in

Isolation and characterization of a human glutathione S-transferase Ha1 subunit gene

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

NAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

retrieved

8 April 2019

stated in

The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

8 April 2019

stated in

Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

8 April 2019

stated in

Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

steroid delta-isomerase activity

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

The role of glutathione in the isomerization of delta 5-androstene-3,17-dione catalyzed by human glutathione transferase A1-1.

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

glutathione transferase activity

determination method

IBA

IDA

IEA

NAS

7 references

retrieved

9 May 2019

stated in

Isolation and characterization of a human glutathione S-transferase Ha1 subunit gene

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

NAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

retrieved

9 May 2019

stated in

The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

9 May 2019

stated in

Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

9 May 2019

stated in

Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IBA

peroxidase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

oxidoreductase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

isomerase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

cell component

cytoplasm

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

extracellular exosome

determination method

IDA

3 references

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

26 September 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

26 September 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IDA

cytosol

determination method

IDA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

extracellular exosome

determination method

HDA

2 references

retrieved

9 May 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

HDA

retrieved

9 May 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

HDA

cytosol

determination method

IBA

IDA

TAS

3 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IBA

biological process

metabolism

determination method

IC

IEA

2 references

retrieved

26 September 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IEA

retrieved

26 September 2017

stated in

Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08263&geneProductId=UniProtKB:P08263

determination method

IC

epithelial cell differentiation

determination method

IEP

1 reference

retrieved

9 May 2019

stated in

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEP

glutathione derivative biosynthetic process

determination method

TAS

1 reference

retrieved

1 January 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

TAS

glutathione metabolic process

determination method

IDA

2 references

retrieved

8 April 2019

stated in

The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

8 April 2019

stated in

Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

cellular oxidant detoxification

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IEA

linoleic acid metabolic process

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

prostaglandin metabolic process

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

glutathione derivative biosynthetic process

determination method

IDA

TAS

2 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

TAS

retrieved

9 May 2019

stated in

Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

glutathione metabolic process

determination method

IBA

IDA

3 references

retrieved

9 May 2019

stated in

The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function

GOA

curator

UniProt

UniProt protein ID

P08263

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

9 May 2019

stated in

Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IBA

xenobiotic metabolic process

determination method

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08263

determination method

IBA

Gene Atlas image

PBB GE GSTA1 203924 at fs.png
732 × 530; 11 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P08263

1 reference

stated in

Identifiers.org

has part(s)

glutathione S-transferase, C-terminal-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08263

Glutathione S-transferase, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08263

Glutathione S-transferase, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08263

Identifiers

RefSeq protein ID

NP_001305988

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2938

NP_665683

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2938

XP_005249091

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2938

UniProt protein ID

P08263

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08263

Ensembl protein ID

ENSP00000335620

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000335620

PDB structure ID

1GSD

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1GSE

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1GSF

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1GUH

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1K3L

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1K3O

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1K3Y

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1PKW

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1PKZ

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1PL1

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1PL2

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1USB

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1XWG

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

1YDK

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

2R3X

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

2R6K

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3I69

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3I6A

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3IK9

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3KTL

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3L0H

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3Q74

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3U6V

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3ZFB

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

3ZFL

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

4HJ2

1 reference

stated in

UniProt

UniProt protein ID

P08263

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

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Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q5572461&oldid=2022908128"