Aldolase, fructose-bisphosphate A (Q5255119)

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mammalian protein found in Homo sapiens

• fructose-1,6-bisphosphate triosephosphate-lyase
• muscle-type aldolase
• fructose-bisphosphate aldolase A
• lung cancer antigen NY-LU-1
• aldolase A, fructose-bisphosphate
• ALDOA
• epididymis secretory sperm binding protein Li 87p

edit

Language	Label	Description	Also known as
English	Aldolase, fructose-bisphosphate A	mammalian protein found in Homo sapiens	fructose-1,6-bisphosphate triosephosphate-lyase muscle-type aldolase fructose-bisphosphate aldolase A lung cancer antigen NY-LU-1 aldolase A, fructose-bisphosphate ALDOA epididymis secretory sperm binding protein Li 87p

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04075

part of

Fructose-bisphosphate aldolase, class-I

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04075

TIM barrel

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04075

Fructose-bisphosphate aldolase class-I active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

Fructose-1,6-bisphosphate aldolase 4ALD wpmp.png
698 × 837; 321 KB

0 references

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04075

encoded by

ALDOA

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04075

molecular function

cytoskeletal protein binding

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

tubulin binding

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

fructose binding

determination method

IDA

2 references

retrieved

9 May 2019

stated in

Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

9 May 2019

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

protein binding

determination method

IPI

2 references

retrieved

9 May 2019

stated in

Proliferating cell nuclear antigen in the cytoplasm interacts with components of glycolysis and cancer

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IPI

retrieved

9 May 2019

stated in

Identification of sperm head proteins involved in zona pellucida binding

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IPI

catalytic activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

lyase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

actin binding

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

Aldolase binding to actin-containing filaments. Formation of paracrystals

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

fructose-bisphosphate aldolase activity

determination method

IEA

EXP

IDA

5 references

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

1 January 2018

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

1 January 2018

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

1 January 2018

stated in

Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

EXP

identical protein binding

determination method

IPI

TAS

2 references

retrieved

31 October 2017

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

TAS

retrieved

31 October 2017

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IPI

RNA binding

determination method

IDA

1 reference

retrieved

31 October 2017

stated in

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

cadherin binding

determination method

IDA

1 reference

retrieved

31 October 2017

stated in

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

RNA binding

determination method

HDA

1 reference

retrieved

9 May 2019

stated in

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

identical protein binding

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

cadherin binding

determination method

HDA

1 reference

retrieved

9 May 2019

stated in

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

fructose-bisphosphate aldolase activity

determination method

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

8 April 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

8 April 2019

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

fructose-bisphosphate aldolase activity

determination method

IBA

IDA

IEA

5 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

9 May 2019

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IBA

cell component

cytoplasm

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

M band

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

membrane

determination method

IDA

1 reference

retrieved

31 October 2017

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

I band

determination method

IEA

TAS

2 references

retrieved

9 May 2019

stated in

Aldolase binding to actin-containing filaments. Formation of paracrystals

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

extracellular region

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

actin cytoskeleton

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

extracellular exosome

determination method

IDA

7 references

retrieved

31 October 2017

stated in

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

31 October 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

31 October 2017

stated in

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

31 October 2017

stated in

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

31 October 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

31 October 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

31 October 2017

stated in

Exosomes with immune modulatory features are present in human breast milk

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

platelet alpha granule lumen

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

nucleus

determination method

IDA

1 reference

retrieved

31 October 2017

stated in

Proteomic characterization of the human sperm nucleus

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

extracellular space

determination method

IDA

1 reference

retrieved

31 October 2017

stated in

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

determination method

IDA

cytosol

determination method

IDA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

secretory granule lumen

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

tertiary granule lumen

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

ficolin-1-rich granule lumen

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

sperm head

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Identification of sperm head proteins involved in zona pellucida binding

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

extracellular space

determination method

HDA

1 reference

retrieved

9 May 2019

stated in

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

nucleus

determination method

HDA

1 reference

retrieved

9 May 2019

stated in

Proteomic characterization of the human sperm nucleus

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

membrane

determination method

HDA

1 reference

retrieved

9 May 2019

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

extracellular exosome

determination method

HDA

IDA

6 references

retrieved

9 May 2019

stated in

Exosomes with immune modulatory features are present in human breast milk

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

9 May 2019

stated in

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

retrieved

9 May 2019

stated in

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

retrieved

9 May 2019

stated in

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

retrieved

9 May 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

retrieved

9 May 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

HDA

cytosol

determination method

IBA

IDA

TAS

3 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IBA

biological process

gluconeogenesis

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

glycolytic process

determination method

IEA

IMP

3 references

retrieved

8 April 2019

stated in

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IMP

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

muscle cell cellular homeostasis

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IMP

canonical glycolysis

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

actin filament organization

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

Aldolase binding to actin-containing filaments. Formation of paracrystals

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

fructose metabolic process

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IMP

platelet degranulation

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

fructose 1,6-bisphosphate metabolic process

determination method

IDA

2 references

retrieved

8 April 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

8 April 2019

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

ATP biosynthetic process

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IMP

regulation of cell shape

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

protein homotetramerization

determination method

ISS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

ISS

striated muscle contraction

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IMP

neutrophil degranulation

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

TAS

binding of sperm to zona pellucida

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Identification of sperm head proteins involved in zona pellucida binding

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IMP

glycolytic process

determination method

IBA

IEA

IMP

4 references

retrieved

9 May 2019

stated in

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IMP

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P04075

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IEA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IBA

fructose 1,6-bisphosphate metabolic process

determination method

IBA

IDA

3 references

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

9 May 2019

stated in

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

determination method

IBA

Gene Atlas image

PBB GE ALDOA 200966 x at fs.png
732 × 530; 12 KB

0 references

has part(s)

Fructose-bisphosphate aldolase class-I active site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P04075

Identifiers

RefSeq protein ID

NP_001121089

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

226

NP_001230106

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

226

NP_908930

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

226

NP_908932

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

226

UniProt protein ID

P04075

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P04075

Ensembl protein ID

ENSP00000400452

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000400452

ENSP00000455700

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000455700

ENSP00000455800

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000455800

ENSP00000378661

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000378661

ENSP00000454499

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000454499

ENSP00000455455

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000455455

ENSP00000455857

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000455857

ENSP00000456020

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000456020

ENSP00000456098

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000456098

ENSP00000457514

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000457514

ENSP00000457643

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000457643

ENSP00000494188

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000494188

ENSP00000496166

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000496166

Freebase ID

/m/0573r8

0 references

Microsoft Academic ID

28165981

0 references

2908643210

0 references

OpenAlex ID

C28165981

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1ALD

1 reference

stated in

UniProt

UniProt protein ID

P04075

retrieved

9 August 2016

language of work or name

English

2ALD

1 reference

stated in

UniProt

UniProt protein ID

P04075

retrieved

9 August 2016

language of work or name

English

4ALD

1 reference

stated in

UniProt

UniProt protein ID

P04075

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(9 entries)

edit

• arwiki الدلس أ
• enwiki Aldolase A
• fawiki آلدولاز A
• frwiki Aldolase A
• ptwiki Aldolase A
• ruwiki Альдолаза A
• svwiki Aldolas A
• ukwiki ALDOA
• zhwiki 醛縮酶A

Wikibooks(0 entries)

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Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

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Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

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