C-X-C motif chemokine ligand 11 (Q5014882)

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mammalian protein found in Homo sapiens

beta-R1
small inducible cytokine B11
Small-inducible cytokine B11
C-X-C motif chemokine 11
chemokine (C-X-C motif) ligand 11
interferon gamma-inducible protein 9
H174
interferon-inducible T-cell alpha chemoattractant
IP-9
I-TAC
small inducible cytokine subfamily B (Cys-X-Cys), member 11
CXCL11
small inducible cytokine subfamily B (Cys-X-Cys), member 9B

Language	Label	Description	Also known as
English	C-X-C motif chemokine ligand 11	mammalian protein found in Homo sapiens	beta-R1 small inducible cytokine B11 Small-inducible cytokine B11 C-X-C motif chemokine 11 chemokine (C-X-C motif) ligand 11 interferon gamma-inducible protein 9 H174 interferon-inducible T-cell alpha chemoattractant IP-9 I-TAC small inducible cytokine subfamily B (Cys-X-Cys), member 11 CXCL11 small inducible cytokine subfamily B (Cys-X-Cys), member 9B

Statements

1 reference

13 November 2019

UniProt protein ID

CXC chemokine 11

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14625

Chemokine interleukin-8-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14625

Chemokine interleukin-8-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CXC Chemokine domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CXC chemokine, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

chemokine activity

determination method

4 references

16 July 2018

Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

16 July 2018

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

cytokine activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

heparin binding

determination method

1 reference

8 April 2019

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

protein binding

determination method

4 references

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

CXCR3 chemokine receptor binding

determination method

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

chemokine activity

determination method

5 references

8 April 2019

Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

intracellular anatomical structure

determination method

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

biological process

determination method

4 references

8 April 2019

Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

positive regulation of leukocyte chemotaxis

determination method

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

T cell chemotaxis

determination method

1 reference

8 April 2019

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

chemokine-mediated signaling pathway

determination method

1 reference

16 July 2018

Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

response to lipopolysaccharide

determination method

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

cell-cell signaling

determination method

1 reference

8 April 2019

Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

positive regulation of release of sequestered calcium ion into cytosol

determination method

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

positive regulation of cAMP-mediated signaling

determination method

1 reference

1 January 2018

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

regulation of cell population proliferation

determination method

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

immune response

determination method

signal transduction

determination method

1 reference

8 April 2019

Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

defense response

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

inflammatory response

determination method

4 references

8 April 2019

Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method

1 reference

21 June 2018

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14625&geneProductId=UniProtKB:O14625

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

adenylate cyclase-activating G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

neutrophil chemotaxis

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

leukocyte chemotaxis

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

chemokine-mediated signaling pathway

determination method

cellular response to lipopolysaccharide

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14625

determination method

Gene Atlas image

PBB GE CXCL11 210163 at fs.png
732 × 530; 11 KB

0 references

http://purl.uniprot.org/uniprot/O14625

1 reference

Identifiers.org

Chemokine interleukin-8-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14625

CXC chemokine, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14625

CXC Chemokine domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14625

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000425819

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425819

ENSP00000306884

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000306884

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

Wikipedia(8 entries)

bswiki CXCL11
cywiki CXCL11
dewiki CXCL11
enwiki CXCL11
shwiki CXCL11
srwiki CXCL11
ukwiki CXCL11
zhwiki CXCL11

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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