Activin A receptor type 2B (Q4650908)

TGFβ superfamily receptor

1 reference

activin types I and II receptor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

protein kinase activity

1 reference

8 April 2019

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13705&geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

protein serine/threonine kinase activity

5 references

8 April 2019

Activation of signalling by the activin receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Activation of signalling by the activin receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Formation and activation by phosphorylation of activin receptor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

transmembrane receptor protein serine/threonine kinase activity

EXP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

7 references

8 April 2019

Modulation of activin signal transduction by inhibin B and inhibin-binding protein (INhBP)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Activation of signalling by the activin receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

protein serine/threonine/tyrosine kinase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

activin receptor activity, type II

1 reference

8 April 2019

Activation of signalling by the activin receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

2 references

transforming growth factor beta-activated receptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

transforming growth factor beta receptor activity, type II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis

growth factor binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

type I transforming growth factor beta receptor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

2 references

1 reference

24 April 2018

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13705&geneProductId=UniProtKB:Q13705

2 references

integral component of plasma membrane

1 reference

24 April 2018

Expression of type II activin receptor genes during differentiation of human K562 cells and cDNA cloning of the human type IIB activin receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13705&geneProductId=UniProtKB:Q13705

protein-containing complex

TAS

1 reference

8 April 2019

Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

activin receptor complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

pattern specification process

biological process

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13705&geneProductId=UniProtKB:Q13705

skeletal system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

roof of mouth development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

regulation of transcription, DNA-templated

1 reference

8 April 2019

Activation of signalling by the activin receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

embryonic foregut morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

positive regulation of bone mineralization

1 reference

8 April 2019

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

skeletal system morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

gastrulation with mouth forming second

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

post-embryonic development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

BMP signaling pathway

3 references

8 April 2019

8 April 2019

ALK1 signaling regulates early postnatal lymphatic vessel development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

8 April 2019

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

odontogenesis of dentin-containing tooth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

protein phosphorylation

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

determination of left/right symmetry

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

positive regulation of osteoblast differentiation

1 reference

8 April 2019

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

positive regulation of activin receptor signaling pathway

IMP

1 reference

8 April 2019

Activation of signalling by the activin receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

regulation of signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

activation of protein kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

1 reference

8 April 2019

Activation of signalling by the activin receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

activin receptor signaling pathway

1 reference

24 April 2018

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13705&geneProductId=UniProtKB:Q13705

transforming growth factor beta receptor signaling pathway

IMP

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13705

serine/threonine-protein kinase, active site

Gene Atlas image

PBB GE ACVR2B 220028 at fs.png
732 × 530; 12 KB

0 references

has part(s)

1 reference

protein kinase domain

1 reference

activin types I and II receptor domain

1 reference