Integrin subunit alpha X (Q4201963)

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mammalian protein found in Homo sapiens

myeloid membrane antigen, alpha subunit
leukocyte surface antigen p150,95, alpha subunit
leukocyte adhesion glycoprotein p150,95 alpha chain
CD11 antigen-like family member C
leukocyte adhesion receptor p150,95
complement component 3 receptor 4 subunit
integrin alpha X
p150 95 integrin alpha chain
Leu M5
integrin, alpha X (complement component 3 receptor 4 subunit)
ITGAX
integrin alpha-X
integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
leu M5, alpha subunit

Language	Label	Description	Also known as
English	Integrin subunit alpha X	mammalian protein found in Homo sapiens	myeloid membrane antigen, alpha subunit leukocyte surface antigen p150,95, alpha subunit leukocyte adhesion glycoprotein p150,95 alpha chain CD11 antigen-like family member C leukocyte adhesion receptor p150,95 complement component 3 receptor 4 subunit integrin alpha X p150 95 integrin alpha chain Leu M5 integrin, alpha X (complement component 3 receptor 4 subunit) ITGAX integrin alpha-X integrin, alpha X (antigen CD11C (p150), alpha polypeptide) leu M5, alpha subunit

Statements

1 reference

13 November 2019

UniProt protein ID

Integrin domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

integrin alpha chain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

von Willebrand factor A-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

Integrin alpha, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

von Willebrand factor, type A, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha beta-propellor, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha-2, protein family

1 reference

based on heuristic

inferred from protein domain or family

FG-GAP repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha chain, C-terminal cytoplasmic region, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

3 references

1 January 2018

Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

1 January 2018

Structure of an integrin with an αI domain, complement receptor type 4

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

1 January 2018

Interactions of TANGO and leukocyte integrin CD11c/CD18 regulate the migration of human monocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

metal ion binding

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

signaling receptor activity

determination method

1 reference

1 January 2018

Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

integral component of membrane

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

determination method

3 references

17 October 2017

Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20702&geneProductId=UniProtKB:P20702

determination method

17 October 2017

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20702&geneProductId=UniProtKB:P20702

determination method

17 October 2017

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20702&geneProductId=UniProtKB:P20702

determination method

plasma membrane

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

secretory granule membrane

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

tertiary granule membrane

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

ficolin-1-rich granule membrane

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

determination method

3 references

1 January 2018

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

1 January 2018

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

1 January 2018

Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

biological process

animal organ morphogenesis

determination method

1 reference

1 January 2018

cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

integrin-mediated signaling pathway

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

heterotypic cell-cell adhesion

determination method

1 reference

1 January 2018

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

determination method

extracellular matrix organization

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

leukocyte migration

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

positive regulation of protein targeting to mitochondrion

determination method

1 reference

17 October 2017

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20702&geneProductId=UniProtKB:P20702

determination method

neutrophil degranulation

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

cytokine-mediated signaling pathway

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20702

determination method

Gene Atlas image

PBB GE ITGAX 210184 at fs.png
732 × 530; 10 KB

0 references

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

von Willebrand factor, type A

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

Integrin alpha chain, C-terminal cytoplasmic region, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

Integrin alpha-2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

Integrin alpha beta-propellor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20702

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000268296

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000268296

ENSP00000454623

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454623

ENSP00000483860

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000483860

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(8 entries)

cywiki ITGAX
dewiki Integrin α-X
enwiki Integrin alpha X
frwiki CD11c
glwiki CD11c
ruwiki Интегрин альфа-X
ttwiki ITGAX
ukwiki ITGAX

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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