dihydrofolate reductase (Q417149)

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mammalian protein found in Homo sapiens
  • DHFR
  • uniprot:P00374
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Language Label Description Also known as
English
dihydrofolate reductase
mammalian protein found in Homo sapiens
  • DHFR
  • uniprot:P00374

Statements

image
PDB 8dfr EBI.jpg
524 × 415; 35 KB
0 references
molecular function
dihydrofolate reductase activity
determination method
NAS
IDA
ISS
IEA
8 references
retrieved
31 January 2018
stated in
The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
NAS
retrieved
31 January 2018
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
ISS
retrieved
31 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
IEA
retrieved
31 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
IEA
retrieved
31 January 2018
stated in
The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and functional
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
IDA
retrieved
31 January 2018
stated in
Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
IDA
retrieved
31 January 2018
stated in
Unusual transient- and steady-state kinetic behavior is predicted by the kinetic scheme operational for recombinant human dihydrofolate reductase
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
IDA
retrieved
31 January 2018
stated in
Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P00374&geneProductId=UniProtKB:P00374
determination method
IDA
dihydrofolate reductase activity
determination method
IBA
IDA
IEA
ISS
NAS
9 references
retrieved
8 April 2019
stated in
The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
IEA
retrieved
8 April 2019
stated in
The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and functional
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
IDA
retrieved
8 April 2019
stated in
Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution
GOA
curator
UniProt
UniProt protein ID
P00374
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
IDA
retrieved
8 April 2019
stated in
Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
IDA
retrieved
8 April 2019
stated in
Unusual transient- and steady-state kinetic behavior is predicted by the kinetic scheme operational for recombinant human dihydrofolate reductase
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00374
determination method
IBA
cell component
biological process

Identifiers

Microsoft Academic ID
2781320022
0 references
2909764806
0 references
PDB structure ID
 
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