hydroxymethylbilane synthase (Q415227)

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mammalian protein found in Homo sapiens

• uroporphyrinogen I synthase
• porphyria, acute; Chester type
• porphobilinogen deaminase
• pre-uroporphyrinogen synthase
• uroporphyrinogen I synthetase
• HMBS

edit

Language	Label	Description	Also known as
English	hydroxymethylbilane synthase	mammalian protein found in Homo sapiens	uroporphyrinogen I synthase porphyria, acute; Chester type porphobilinogen deaminase pre-uroporphyrinogen synthase uroporphyrinogen I synthetase HMBS

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08397

Wikimedia disambiguation page

1 reference

imported from Wikimedia project

English Wikipedia

part of

Porphobilinogen deaminase, C-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08397

porphobilinogen deaminase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08397

Porphobilinogen deaminase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Porphobilinogen deaminase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Porphobilinogen deaminase, dipyrromethane cofactor binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08397

encoded by

HMBS

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08397

molecular function

transferase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

hydroxymethylbilane synthase activity

determination method

IDA

IEA

TAS

5 references

retrieved

27 March 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08397&geneProductId=UniProtKB:P08397

determination method

TAS

retrieved

27 March 2018

stated in

Studies on the mechanism of hydroxymethylbilane synthase concerning the role of arginine residues in substrate binding

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08397&geneProductId=UniProtKB:P08397

determination method

TAS

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08397&geneProductId=UniProtKB:P08397

determination method

IEA

retrieved

27 March 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08397&geneProductId=UniProtKB:P08397

determination method

IEA

retrieved

27 March 2018

stated in

Human uroporphyrinogen III synthase: NMR-based mapping of the active site

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08397&geneProductId=UniProtKB:P08397

determination method

IDA

hydroxymethylbilane synthase activity

determination method

IBA

IDA

IEA

TAS

5 references

retrieved

8 April 2019

stated in

Studies on the mechanism of hydroxymethylbilane synthase concerning the role of arginine residues in substrate binding

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

retrieved

8 April 2019

stated in

Human uroporphyrinogen III synthase: NMR-based mapping of the active site

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IBA

cell component

cytosol

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

TAS

cytoplasm

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IBA

biological process

protoporphyrinogen IX biosynthetic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

tetrapyrrole biosynthetic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

porphyrin-containing compound biosynthetic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

peptidyl-pyrromethane cofactor linkage

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

heme biosynthetic process

determination method

IBA

IC

IEA

TAS

4 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IEA

retrieved

8 April 2019

stated in

Human uroporphyrinogen III synthase: NMR-based mapping of the active site

GOA

curator

UniProt

UniProt protein ID

P08397

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IC

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08397

determination method

IBA

Gene Atlas image

PBB GE HMBS 203040 s at fs.png
732 × 530; 11 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P08397

1 reference

stated in

Identifiers.org

has part(s)

Porphobilinogen deaminase, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08397

Porphobilinogen deaminase, dipyrromethane cofactor binding site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08397

Porphobilinogen deaminase, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08397

Identifiers

RefSeq protein ID

NP_000181

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

NP_001019553

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

NP_001245137

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

NP_001245138

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

XP_005271588

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

XP_005271589

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

XP_005271590

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

XP_011541098

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

XP_016873118

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

XP_024304228

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

3145

UniProt protein ID

P08397

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08397

Ensembl protein ID

ENSP00000376584

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000376584

ENSP00000392041

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000392041

ENSP00000438424

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000438424

ENSP00000443058

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000443058

ENSP00000444730

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000444730

ENSP00000445599

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000445599

ENSP00000445429

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000445429

ENSP00000438726

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000438726

ENSP00000444817

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000444817

ENSP00000442079

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000442079

ENSP00000491061

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000491061

ENSP00000439904

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000439904

ENSP00000444849

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000444849

ENSP00000497255

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000497255

ENSP00000498044

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000498044

ENSP00000497548

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000497548

ENSP00000498079

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000498079

ENSP00000496970

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000496970

ENSP00000498786

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000498786

Freebase ID

/m/0f31w0

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

2778503633

0 references

OpenAlex ID

C2778503633

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

3ECR

1 reference

stated in

UniProt

UniProt protein ID

P08397

retrieved

9 August 2016

language of work or name

English

3EQ1

1 reference

stated in

UniProt

UniProt protein ID

P08397

retrieved

9 August 2016

language of work or name

English

UMLS CUI

C0032706

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

24 May 2023

 

Sitelinks

Wikipedia(12 entries)

edit

• bswiki HMBS
• cywiki HMBS
• dewiki Porphobilinogen-Desaminase
• enwiki Porphobilinogen deaminase
• eswiki HMBS
• fiwiki Porfobilinogeenideaminaasi
• itwiki Porfobilinogeno deaminasi
• jawiki ポルフォビリノーゲンデアミナーゼ
• lawiki Porphobilinogeni deaminasis
• shwiki Hidroksimetilbilan sintaza
• srwiki Hidroksimetilbilan sintaza
• ukwiki HMBS

Wikibooks(0 entries)

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Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q415227&oldid=2117251726"