The Hallmarks of Cancer (Q221226)

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Europe PubMed Central

title

The Hallmarks of Cancer (English)

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1

D Hanahan

D

Hanahan

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27 July 2022

2

R A Weinberg

R A

Weinberg

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27 July 2022

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language of work or name

English

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publication date

January 2000

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described at URL

language of work or name

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100

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page(s)

57–70

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issue

1

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cites work

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How tumors become angiogenic

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The INK4a/ARF tumor suppressor: one gene--two products--two pathways

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A matter of life and cell death

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Mitochondria and apoptosis

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Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

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Creation of human tumour cells with defined genetic elements

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Telomerase activity is sufficient to allow transformed cells to escape from crisis

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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Lessons from hereditary colorectal cancer

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ONCOGENESIS: Landscaping the Cancer Terrain

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Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes

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Genetic instabilities in human cancers

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p53, the cellular gatekeeper for growth and division

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Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

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Oncogenes as inducers of tumor angiogenesis

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How many mutations are required for tumorigenesis? Implications from human cancer data

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Ras--a versatile cellular switch

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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A survey of telomerase activity in human cancer

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Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas

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Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

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p53-dependent apoptosis suppresses tumor growth and progression in vivo

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Caspases: enemies within

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

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The retinoblastoma protein and cell cycle control

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ECM and cell surface proteolysis: regulating cellular ecology

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The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

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Cell death: the significance of apoptosis

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Growth factor receptor tyrosine kinases

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Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

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Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

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28 October 2013

Microsoft Academic ID

2776199265

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100280

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference