parathyroid hormone like hormone (Q2007821)

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mammalian protein found in Homo sapiens

• osteostatin
• PTH-related protein
• PLP
• parathyroid hormone-related protein
• parathyroid hormone-like related protein
• parathyroid hormone-like hormone preproprotein
• PTHLH
• PTH-rP
• Parathyroid hormone-like protein

edit

Language	Label	Description	Also known as
English	parathyroid hormone like hormone	mammalian protein found in Homo sapiens	osteostatin PTH-related protein PLP parathyroid hormone-related protein parathyroid hormone-like related protein parathyroid hormone-like hormone preproprotein PTHLH PTH-rP Parathyroid hormone-like protein

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

18 December 2019

UniProt protein ID

P12272

subclass of

protein precursor

0 references

part of

Parathyroid hormone-related protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P12272

image

Protein PTHLH PDB 1bzg.png
614 × 178; 37 KB

0 references

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

18 December 2019

UniProt protein ID

P12272

encoded by

PTHLH

1 reference

stated in

UniProt

retrieved

18 December 2019

UniProt protein ID

P12272

molecular function

peptide hormone receptor binding

determination method

IDA

1 reference

retrieved

16 July 2018

stated in

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

GOA

curator

UniProt

UniProt protein ID

P12272

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12272&geneProductId=UniProtKB:P12272

determination method

IDA

hormone activity

determination method

IBA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

Characterization of the human parathyroid hormone-like peptide gene. Functional and evolutionary aspects

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P12272

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IBA

peptide hormone receptor binding

determination method

IBA

IDA

2 references

retrieved

8 April 2019

stated in

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

GOA

curator

UniProt

UniProt protein ID

P12272

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IBA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IPI

cell component

extracellular region

determination method

TAS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P12272

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

nucleus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P12272

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

Golgi apparatus

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

nucleoplasm

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

extracellular space

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Effect of endogenously produced parathyroid hormone-related peptide on growth of a human hepatoma cell line (Hep G2)

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

cytoplasm

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

Enhanced growth of MCF-7 breast cancer cells overexpressing parathyroid hormone-related peptide

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P12272

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

cytosol

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

biological process

regulation of gene expression

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The immune response of Lewis rats to peptide 68-88 of guinea pig myelin basic protein. I. T cell determinants

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

skeletal system development

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

osteoblast development

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IBA

cell-cell signaling

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Purification and characterization of recombinant human parathyroid hormone-related protein

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

female pregnancy

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Parathyroid hormone-related protein(1-34) in gestational fluids and release from human gestational tissues

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

negative regulation of chondrocyte differentiation

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The immune response of Lewis rats to peptide 68-88 of guinea pig myelin basic protein. I. T cell determinants

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

adenylate cyclase-activating G protein-coupled receptor signaling pathway

determination method

IDA

1 reference

retrieved

16 July 2018

stated in

The parathyroid hormone (PTH)/PTH-related peptide receptor mediates actions of both ligands in murine bone

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12272&geneProductId=UniProtKB:P12272

determination method

IDA

cAMP metabolic process

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Purification and characterization of recombinant human parathyroid hormone-related protein

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

positive regulation of cell population proliferation

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Endogenous parathyroid hormone-related peptide enhances proliferation and inhibits differentiation in the osteoblast-like cell line ROS 17/2.8

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

negative regulation of cell population proliferation

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

epidermis development

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

regulation of signaling receptor activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

G protein-coupled receptor signaling pathway

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

TAS

bone mineralization

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IEA

negative regulation of chondrocyte development

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

The immune response of Lewis rats to peptide 68-88 of guinea pig myelin basic protein. I. T cell determinants

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

adenylate cyclase-activating G protein-coupled receptor signaling pathway

determination method

IBA

IDA

2 references

retrieved

8 April 2019

stated in

The parathyroid hormone (PTH)/PTH-related peptide receptor mediates actions of both ligands in murine bone

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12272

determination method

IBA

Gene Atlas image

PBB GE PTHLH 206300 s at fs.png
732 × 530; 10 KB

0 references

has part(s)

PTHrP(1-36)

0 references

Identifiers

MeSH descriptor ID

D044162

subject named as

Parathyroid Hormone-Related Protein

0 references

MeSH tree code

D06.472.699.591

0 references

D12.644.276.908

0 references

D12.644.548.588

0 references

D12.776.467.890

0 references

D23.529.890

0 references

RefSeq protein ID

NP_002811

1 reference

stated in

NCBI Gene

retrieved

27 December 2019

Entrez Gene ID

5744

NP_945315

1 reference

stated in

NCBI Gene

retrieved

27 December 2019

Entrez Gene ID

5744

NP_945316

1 reference

stated in

NCBI Gene

retrieved

27 December 2019

Entrez Gene ID

5744

NP_945317

1 reference

stated in

NCBI Gene

retrieved

27 December 2019

Entrez Gene ID

5744

XP_011519076

1 reference

stated in

NCBI Gene

retrieved

27 December 2019

Entrez Gene ID

5744

XP_016875164

1 reference

stated in

NCBI Gene

retrieved

27 December 2019

Entrez Gene ID

5744

UniProt protein ID

P12272

1 reference

stated in

UniProt

retrieved

18 December 2019

UniProt protein ID

P12272

Ensembl protein ID

ENSP00000441890

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000441890

ENSP00000201015

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000201015

ENSP00000379209

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000379209

ENSP00000379213

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000379213

ENSP00000440613

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000440613

ENSP00000441571

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000441571

ENSP00000441765

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000441765

ENSP00000444519

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000444519

ENSP00000445157

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000445157

Freebase ID

/m/02qbdl

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

2778828131

0 references

OpenAlex ID

C2778828131

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

3H3G

1 reference

stated in

UniProt

UniProt protein ID

P12272

retrieved

21 March 2016

language of work or name

English

1BZG

1 reference

stated in

UniProt

UniProt protein ID

P12272

retrieved

21 March 2016

language of work or name

English

1M5N

1 reference

stated in

UniProt

UniProt protein ID

P12272

retrieved

21 March 2016

language of work or name

English

3FFD

1 reference

stated in

UniProt

UniProt protein ID

P12272

retrieved

21 March 2016

language of work or name

English

Semantic Scholar topic ID

48262

0 references

UMLS CUI

C0070099

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(8 entries)

edit

• arwiki البروتين المرتبط بالهرمون الدريقي
• azwiki Paratiroid hormonu ilə əlaqəli zülal
• enwiki Parathyroid hormone-related protein
• itwiki Peptide correlato al paratormone
• plwiki Peptyd PTH-podobny
• shwiki Paratiroidnom hormonu srodan protein
• srwiki Paratiroidnom hormonu srodan protein
• svwiki Bisköldkörtelhormonrelaterat protein

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q2007821&oldid=2022903633"