insulin like growth factor 1 receptor (Q2005209)

Protein kinase-like domain superfamily

1 reference

tyrosine-protein kinase, insulin-like receptor

1 reference

Fibronectin type III superfamily

1 reference

Growth factor receptor cysteine-rich domain superfamily

1 reference

Receptor L-domain superfamily

1 reference

Fibronectin type III, protein family

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Receptor L-domain, protein family

1 reference

Furin-like cysteine-rich domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, receptor class II, conserved site, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

Furin-like repeat, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

protein kinase activity

1 reference

8 April 2019

insulin-like growth factor binding

2 references

8 April 2019

Interaction of the .alpha..beta. dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

insulin receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

1 reference

8 April 2019

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

insulin-like growth factor-activated receptor activity

28 references

8 April 2019

Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

14-3-3 binding to the IGF-1 receptor is mediated by serine autophosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

JAK/STAT3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Interaction in vitro of the product of the c-Crk-II proto-oncogene with the insulin-like growth factor I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Fine details of IGF-1R activation, inhibition, and asymmetry determined by associated hydrogen /deuterium-exchange and peptide mass mapping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Interaction of the molecular weight 85K regulatory subunit of the phosphatidylinositol 3-kinase with the insulin receptor and the insulin-like growth factor-1 (IGF- I) receptor: comparative study using the yeast two-hybrid system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

A comprehensive resource of interacting protein regions for refining human transcription factor networks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Interaction of SH2-containing protein tyrosine phosphatase 2 with the insulin receptor and the insulin-like growth factor-I receptor: studies of the domains involved using the yeast two-hybrid system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Monitoring the activation state of insulin/insulin-like growth factor-1 hybrid receptors using bioluminescence resonance energy transfer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Interaction of p85 subunit of PI 3-kinase with insulin and IGF-1 receptors analysed by using the two-hybrid system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Hypoxia-induced SM22α in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo- and radiation therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Monitoring the activation state of the insulin-like growth factor-1 receptor and its interaction with protein tyrosine phosphatase 1B using bioluminescence resonance energy transfer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

identical protein binding

IPI

3 references

8 April 2019

Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Intracellular association of a mutant insulin-like growth factor receptor with endogenous receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Fine details of IGF-1R activation, inhibition, and asymmetry determined by associated hydrogen /deuterium-exchange and peptide mass mapping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

transmembrane receptor protein tyrosine kinase activity

IPI

2 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

protein tyrosine kinase activity

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Regulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblasts

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

2 references

insulin-like growth factor I binding

transmembrane receptor protein tyrosine kinase activity

IPI

insulin-activated receptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

insulin receptor substrate binding

3 references

8 April 2019

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

intracellular membrane-bounded organelle

1 reference

8 April 2019

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

1 reference

3 January 2017

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

integral component of plasma membrane

1 reference

3 January 2017

Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

alphav-beta3 integrin-IGF-1-IGF1R complex

IC

1 reference

8 April 2019

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

integral component of plasma membrane

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IC

insulin receptor complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

insulin receptor signaling pathway

biological process

1 reference

3 January 2017

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

insulin-like growth factor receptor signaling pathway

1 reference

3 January 2017

Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

positive regulation of cell migration

1 reference

8 April 2019

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

negative regulation of apoptotic process

Interaction of the .alpha..beta. dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation

protein tetramerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

positive regulation of DNA replication

1 reference

3 January 2017

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

protein phosphorylation

1 reference

8 April 2019

regulation of JNK cascade

1 reference

3 January 2017

Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1)

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

1 reference

8 April 2019

Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

positive regulation of cell population proliferation

1 reference

3 January 2017

Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P08069

peptidyl-tyrosine autophosphorylation

1 reference

8 April 2019

Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

protein autophosphorylation

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

8 April 2019

Interaction of the .alpha..beta. dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

phosphatidylinositol-mediated signaling

IC

1 reference

8 April 2019

Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

1 reference

8 April 2019

Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

positive regulation of cell population proliferation

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

positive regulation of protein-containing complex disassembly

1 reference

8 April 2019

Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

positive regulation of MAPK cascade

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

insulin-like growth factor receptor signaling pathway

anatomical structure development

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

positive regulation of protein kinase B signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

cellular response to glucose stimulus

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

dendritic spine maintenance

1 reference

8 April 2019

Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}

ISS

amyloid-beta clearance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

positive regulation of cold-induced thermogenesis

1 reference

8 April 2019

Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

cellular response to amyloid-beta

ISS

1 reference

8 April 2019

Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-β peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08069

physically interacts with

IGI

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7397

IUPHAR/BPS Guide to PHARMACOLOGY

17 August 2016

1 reference

Guide to Pharmacology Ligand ID

7741

17 August 2016

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL575448

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL283120

Gene Atlas image

PBB GE IGF1R 203627 at fs.png
732 × 530; 11 KB

0 references

has part(s)

tyrosine-protein kinase, active site

1 reference

fibronectin type III

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

Receptor L-domain

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

Furin-like cysteine-rich domain

1 reference

Furin-like repeat

1 reference

tyrosine-protein kinase, receptor class II, conserved site

1 reference

D08.811.913.696.620.682.725.400.185

Identifiers

MeSH descriptor ID

D017526

subject named as

Receptor, IGF Type 1

0 references

MeSH tree code

0 references

D12.776.543.750.630.468

0 references

D12.776.543.750.750.400.780.400

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016